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However, targeting metabolic pathways may lead to unintended toxicity in normal cells that share similar metabolic dependencies with tumor cells

In this regard, topical triple combination therapy containing hydroquinone 4%, tretinoin 0.05%, and fluocinolone 0.01% have received the Food and Drug Administration (FDA) approval in melasma management

10.1007/s11901-006-0019-7 [DOI] [PubMed] [Google Scholar] Castelli M

The Role of P450 Enzymes in Detoxification and Methylation Pathways In addition to the previously discussed detoxification pathways of methylation and glutathione, P450 enzymes also play a crucial role in detoxification

L-Carnitine 1500 by Nutrakey: Powering Your Fitness Journey